Table 3. ROC analysis of the 5 nephrotoxicity biomarkers at the screening stage.
Biomarkers | AUC a | Sensitivity (%) | Specificity (%) | Standard error b | 95% CI |
|
Lower | Upper | |||||
Thymidine | 0.901 | 0.956 | 0.714 | 0.044 | 0.815 | 0.988 |
LysoPC(16:1) | 0.817 | 0.813 | 0.786 | 0.069 | 0.682 | 0.952 |
LysoPC(18:4) | 0.806 | 0.846 | 0.714 | 0.064 | 0.680 | 0.933 |
LysoPC(20:5) | 0.886 | 0.791 | 0.857 | 0.033 | 0.821 | 0.951 |
LysoPC(22:5) | 0.830 | 0.758 | 0.786 | 0.062 | 0.710 | 0.951 |
aThe area under the curve.
bUnder the nonparametric assumption.