Fig. 4. Pathway analysis (STRING): networks created from proteins differentially regulated in male and female rats (controls) in ET animals (A) or HT rats (B). Members from pathways related to Glycolysis/Gluconeogenesis (Glyco), Fatty acid metabolism (FA), Drug metabolism or Metabolism of xenobiotics by cytochrome P450 (CYP), Glutathione metabolism (GSH) are boxed. Boxes are displayed in colour. Further details on pathways and gene/protein names are compiled in ESI Table 3.† .