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. 2017 Sep 8;6(6):772–794. doi: 10.1039/c7tx00184c

Table 1. Some plants used to treat women's health conditions and their major phytoestrogen(s).

Plant origin (Latin name) Major phytoestrogen(s) Suggested use/condition
Black cohosh (Cimicifuga racemosa) Actein, 23-epi-26-deoxyactein a Enhanced fertility, premenstrual syndrome, menopausal symptoms; relieve menstrual cramps, aid amenorrhea and to ease labor
Chaste berry (Vitex agnus castus) Casticin, isoorientin, apigenin, penduletin Heavy menstrual bleeding, endometriosis, fertility problems
Citrus spp. Naringenin, naringin Weight gain during menopause
Flaxseed (Linum usitatissimum) Enterodiol, enterolactone b Heavy menstrual bleeding
Hop (Humulus lupulus) 8-Prenylnaringenin, 6-prenylnaringenin, isoxantohumol Breast enhancement, menopausal symptoms
Maca (Lepidium meyenii) Campesterol, beta-sitosterol Enhanced fertility and sexual behavior, menstrual problems
Red clover (Trifolium pratense) Biochanin A, formononetin Menopausal symptoms, including hot flashes
Soy (Glycine max) Genistein, daidzein Menopausal symptoms
Wild yam (Dioscorea villosa) Diosgenin Menstrual cramping, irregular menstrual cycles, pregnancy-related nausea and morning sickness
Ginseng (Panax ginseng) Ginsenosides, naringenin, chlorogenic acid Anti-ageing, cardioprotective
St John's wort (Hypericum perforatum) (pseudo)Hypericin, quercetin, rutin Premenstrual syndrome, menopausal symptoms
Grape (Vitis spp.), blueberry (Vaccinium spp.) Resveratrol Reduce hot flashes, cardioprotective, prevention of osteoporosis

aExact phytoestrogen content is unclear. Although some earlier studies report the presence of formononetin in black cohosh extracts (BCE), most studies describe that formononetin could not be determined in BCE.11

bMammalian phytoestrogens which are formed upon conversion of plant lignans matairesinol and secoisolariciresinol by gut microbiota.12