Fig. 1. Ultrastructure images of mitochondria incubated with varied concentrations of Ag⁺ measured by TEM. (A) Control, the compact inner membrane and distinguishable cristae indicate that fresh mitochondria isolated from rat liver were intact in structure. (B) 2 μM Ag⁺, an obvious matrix swelling took place. (C) 10 μM Ag⁺, the swelling aggravated and there was a remarkable separation between the outer and inner membrane. (D) 50 μM Ag⁺, mitochondria were badly damaged.