MAPK |
DUSP8, MEF2C, MAP3 K1, MAP2 K3, SOS2, CRKL, DUSP6, FLNB, MAP3 K3, NRAS, PPP3CA, PRKX, TAOK1, RASA1, TGFBR2, MAP4 K4, RAPGEF2, EGFR, TAB2, FOS, KRAS, RAC1, RPS6KA3, MAP3 K14
|
PI3K-Akt |
PIK3R1, SOS2, IRS1, ITGB8, MDM2, NRAS, RPS6KB1, CREB3L2, EGFR, SGK3, KRAS, PKN2, RAC1, YWHAE, CCND2
|
Jak-STAT |
SPRY2, IL12A, PIK3R1, SOS2, STAT3, IFNGR2, CBL, SOCS5, CCND2
|
FoxO |
PIK3R1, SOS2, STAT3, MDM2, S1PR1, EGFR, SGK3, GABARAPL1, KRAS, SMAD2, CCND2
|
Cytokine–cytokine |
IL12A, CCL1, IFNGR2, TNFRSF11B, TGFBR2, TNFRSF10A, ACVR1B, ACVR2A, EGFR, IL17RB
|
Chemokine |
PIK3R1, CCL1, SOS2, STAT3, TIAM1, CRKL, NRAS, PRKX, PXN, KRAS, RAC1
|
TNF |
DNM1L, JAG1, PIK3R1, MAP2 K3, CREB3L2; CEBPB, TAB2, FOS, MAP3 K14
|
cAMP |
ATP2B4, PIK3R1, TIAM1, PRKX, CREB3L2, FOS, GNAS, RAC1
|
TGF-beta |
SMAD3, SMAD5, RPS6KB1, SKP1, TGFBR2, ACVR1B, ACVR2A, ZFYVE9
|
HIF-1α |
PIK3R1, STAT3, IFNGR2, RPS6KB1, EGFR, HIF1A
|
Toll-like receptor |
IL12A, PIK3R1, MAP2 K3, TAB2, FOS, RAC1
|
Inflammatory mediator regulation of TRP channels |
GNAS, PRKX, PIK3R1, MAP2 K3
|
p53 |
CCND2, MDM2
|