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. 2016 May 25;5(4):1012–1016. doi: 10.1039/c6tx00130k

Table 2. Synopsis of in vitro biological data and calculated octanol/water partition coefficients (log P).

Compound	IC₅₀ RBC-AChE ± SEM ^a (μM)	log P	IC₅₀ CHO-K1 ± SEM ^a (mM)	IC₅₀ HepG2 ± SEM ^a (mM)
5	2.47 ± 0.13	–1.65	5.0 ± 0.7	1.21 ± 0.08
Pralidoxime	217 ± 17	–3.26	32.0 ± 3.4	23.59 ± 0.52
Obidoxime	197 ± 8	–6.93	12.0 ± 1.6	4.02 ± 0.28
7-MEOTA	10.0 ± 1.0	0.66	0.063 ± 0.004	0.0115 ± 0.0003
4-PA	>100	–0.51	15.8 ± 1.6	13.19 ± 1.47

^aResults are expressed as the mean of at least two independent experiments.