Table 1.

Functions of the 12 T cell antigens mutated in both L5 and L6.

T cell antigen	Function
Rv0288	encodes low molecular weight antigen 7 EsxH involved with cell wall and cell processes
Rv0934	encodes periplasmic phosphate-binding lipoprotein PstS1 involved with cell wall and cell processes
Rv2029c	encodes 6-phosphofructokinase PfkB involved with intermediate metabolism and respiration
Rv2627c	encoding a conserved hypothetical protein
Rv3003c	Encodes the large subunit of acetolactate synthase involved with valine and isoleucine biosynthesis
Rv3024c	encodes a probable tRNA involved with information pathways
Rv3763	encodes a 19 kDa lipoprotein antigen precursor LpqH involved with cell wall and cell processes
Rv3804c	encodes the secreted antigen 85-a FbpA involved with lipid metabolism
Rv3823c	encodes conserved integral membrane transport protein MmpL8 involved with cell wall and cell processes
Rv3825c	encodes polyketide synthase Pks2 involved with lipid metabolism
Rv3879c	encodes ESX-1 secretion-associated protein EspK involved with cell wall and cell processes
Rv3883c	encodes membrane-anchored myosin MycP1 involved with intermediate metabolism and respiration