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. 2018 Jul 26;9:2930. doi: 10.1038/s41467-018-05344-9

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Backtracking dynamics. a Analysis of backtracking events. The trace shown contains a backtracking event occurring at site ‘b’. The backtrack depth, pre-backtrack time and backtrack duration are shown. b Histogram of backtracking events by position (blue). Gray zones in the figure indicate the ± 3 bp region surrounding each major pause site. c Backtracking depths and times measured at opposing forces for site ‘b’. d Histogram of pre-backtrack times measured at site ‘b’ at opposing forces