Table 2.
Genotype and allele frequencies of the MIF −173GC variant in patients and controls
| MIF | Patients (n = 111), n (%) | Controls (n = 100), n (%) | p | OR (95% CI) |
|---|---|---|---|---|
| Genotypes | ||||
| GG | 49 (44.14) | 58 (58) | 1.31 (0.82–2.1) | |
| GC | 44 (39.63) | 38 (38) | 0.008 | 0.95 (0.57–1.60) |
| CC | 18 (16.21) | 4 (4) | 0.24 (0.05–0.78) | |
| HWE | 0.139 | 0.466 | ||
| GG:GC + CC | 49 (44.14):62 (55.85) | 58 (58):42 (42) | >0.05 | 0.57 (0.31–1.02) |
| GG + GC:CC Alleles | 93 (83.78):18 (16.21) | 96 (96):4 (4) | 0.003 | 0.21 (0.06–0.63) |
| G | 142 (69.98) | 154 (77) | >0.05 | 1.10 (0.74–.63) |
| C | 80 (36.03) | 46 (23) |
Data were analyzed by χ2 test. If p < 0.05 – not consistent with Hardy-Weinberg equilibrium (HWE). The results that are statistically significant are shown in italics.