TABLE 1.

Target genes/regions and reason for inclusion in the reduced M. tuberculosis bait set

Gene target and/or region	Region property
gyrB/gyrA	Fluoroquinolone resistance
rpoB/rpoC	Rifampin resistance
rpsL	Streptomycin resistance
rrs	Streptomycin, amikacin, and kanamycin resistance
gidB	Streptomycin resistance
mabA-fabG1, inhA, and promoter	Isoniazid and ethionamide resistance
katG	Isoniazid resistance
kasA	Isoniazid resistance
aphC-oxyR	Isoniazid resistance
tlyA	Capreomycin resistance
pncA and promoter	Pyrazinamide resistance
eis and promoter	Kanamycin resistance
thyA	PAS resistance
embC	Ethambutol resistance
embB	Ethambutol resistance
ethA	Ethionamide resistance
Direct repeat locus	Spoligotyping