TABLE 2.

Characteristics of enrolled subjects according to composite reference standard

Characteristic	No. of patients	No. (%) of patients							P value
		Definite LTBIa with positive results by:			Possible LTBI with positive results by:			Not LTBI (n = 152)
		QFT-GITb and QFT-Plusc (n = 53)	QFT-GIT only (n = 3)	QFT-Plus only (n = 10)	QFT-GIT and QFT-Plus (n = 4)	QFT-GIT only (n = 3)	QFT-Plus only (n = 4)
Age (yr)									0.001
60–64	9	3 (33.3)				2 (22.2)		4 (44.4)
65–74	34	9 (26.5)	1 (2.9)	1 (2.9)		1 (2.9)		22 (64.7)
75–84	108	24 (22.2)	2 (1.9)	4 (3.7)	3 (2.8)		4 (3.7)	71 (65.7)
≥85	78	17 (21.8)		5 (6.4)	1 (1.3)			55 (70.5)
Sex									0.561
Female	112	24 (21.4)	2 (1.8)	3 (2.7)	1 (0.9)	2 (1.8)	1 (0.9)	79 (70.5)
Male	117	29 (24.8)	1 (0.9)	7 (6.0)	3 (2.6)	1 (0.9)	3 (2.6)	73 (62.4)
Body mass index									0.807
<18.5	52	10 (19.2)		2 (3.8)			1 (1.9)	39 (75.0)
18.5–24	117	31 (26.5)	2 (1.7)	6 (5.1)	3 (2.6)	2 (1.7)	3 (2.6)	70 (59.8)
>24	60	12 (20.0)	1 (1.7)	2 (3.3)	1 (1.7)	1 (1.7)		43 (71.7)
Smoking									0.644
Never	168	38 (22.6)	2 (1.2)	6 (3.6)	2 (1.2)	3 (1.8)	3 (1.8)	114 (67.9)
Ever	51	11 (21.6)	1 (2.0)	4 (7.8)	1 (2.0)		1 (2.0)	33 (64.7)
Current	10	4 (40.0)			1 (10.0)			5 (50.0)
Barthel index									0.742
<40	101	20 (19.8)	1 (1.0)	4 (4.0)	1 (1.0)	1 (1.0)	3 (3.0)	71 (70.3)
41–59	51	14 (27.5)	1 (2.0)	1 (2.0)	2 (3.9)			33 (64.7)
>60	77	19 (24.7)	1 (1.3)	5 (6.5)	1 (1.3)	2 (2.6)	1 (1.3)	48 (62.3)
BCG vaccination									0.631
No	96	21 (21.9)	1 (1.0)	6 (6.3)	2 (2.1)		1 (1.0)	65 (67.7)
Yes	133	32 (24.1)	2 (1.5)	4 (3.0)	2 (1.5)	3 (2.3)	3 (2.3)	87 (65.4)
Comorbidities
Hypertension									0.392
No	87	26 (29.9)	1 (1.1)	5 (5.7)	1 (1.1)	2 (2.3)	1 (1.1)	51 (58.6)
Yes	142	27 (19.0)	2 (1.4)	5 (3.5)	3 (2.1)	1 (0.7)	3 (2.1)	101 (71.1)
Diabetes mellitus									0.757
No	155	40 (25.8)	2 (1.3)	8 (5.2)	3 (1.9)	2 (1.3)	3 (1.9)	97 (62.6)
Yes	74	13 (17.6)	1 (1.4)	2 (2.7)	1 (1.4)	1 (1.4)	1 (1.4)	55 (74.3)
Dementia									0.393
No	165	37 (22.4)	3 (1.8)	10 (6.1)	3 (1.8)	2 (1.2)	2 (1.2)	108 (65.5)
Yes	64	16 (25.0)			1 (1.6)	1 (1.6)	2 (3.1)	44 (68.8)
Cerebral vascular accident									0.959
No	154	33 (21.4)	2 (1.3)	7 (4.5)	3 (1.9)	2 (1.3)	2 (1.3)	105 (68.2)
Yes	75	20 (26.7)	1 (1.3)	3 (4.0)	1 (1.3)	1 (1.3)	2 (2.7)	47 (62.7)
Heart disease									0.066
No	188	42 (22.3)	3 (1.6)	9 (4.8)	1 (0.5)	3 (1.6)	4 (2.1)	126 (67.0)
Yes	41	11 (26.8)		1 (2.4)	3 (7.3)			26 (63.4)
Parkinsonism									0.764
No	210	49 (23.3)	3 (1.4)	10 (4.8)	3 (1.4)	3 (1.4)	4 (1.9)	138 (65.7)
Yes	19	4 (21.1)			1 (5.3)			14 (73.7)
Chronic obstructive pulmonary disease
No	215	50 (23.3)	3 (1.4)	10 (4.7)	4 (1.9)	3 (1.4)	3 (1.4)	142 (66.0)
Yes	14	3 (21.4)					1 (7.1)	10 (71.4)
Other									0.457
No	161	36 (22.4)	1 (0.6)	9 (5.6)	2 (1.2)	2 (1.2)	2 (1.2)	109 (67.7)
Yes	68	17 (25.0)	2 (2.9)	1 (1.5)	2 (2.9)	1 (1.5)	2 (2.9)	43 (63.2)
Laboratory tests
HbA1C (%)									0.260
<6.5	189	46 (24.3)	2 (1.1)	9 (4.8)	4 (2.1)	1 (0.5)	3 (1.6)	124 (65.6)
≥6.5	40	7 (17.5)	1 (2.5)	1 (2.5)		2 (5.0)	1 (2.5)	28 (70.0)
Creatinine (mg/dl)
<1.5	199	47 (23.6)	3 (1.5)	9 (4.5)	2 (1.0)	3 (1.5)	3 (1.5)	132 (66.3)
≥1.5	30	6 (20.0)		1 (3.3)	2 (6.7)		1 (3.3)	20 (66.7)
Alanine transaminase (U/liter)									0.378
<35	212	49 (23.1)	3 (1.4)	10 (4.7)	4 (1.9)	3 (1.4)	4 (1.9)	139 (65.6)
≥35	17	4 (23.5)						13 (76.5)
Albumin (g/dl)									0.402
<3.5	57	10 (17.5)		2 (3.5)	2 (3.5)		2 (3.5)	41 (71.9)
≥3.5	172	43 (25.0)	3 (1.7)	8 (4.7)	2 (1.2)	3 (1.7)	2 (1.2)	111 (64.5)

^aLTBI, latent TB infection.

^bQFT-GIT, QuantiFERON-TB Gold In-Tube.

^cQFT-Plus, QuantiFERON-TB Gold Plus.