TABLE 1.
Patient characteristics at the time of Corynebacterium species respiratory isolation
| Characteristicsa | No. (%) of patients (n = 24) |
|---|---|
| Male sex | 13 (54) |
| Age (median years [IQR]) | 57.5 [49.4–61.2] |
| Pretransplant diagnosis | |
| IPF | 13 (54) |
| COPD | 10 (42) |
| Hemangiomatosis | 1 (4) |
| Transplant type | |
| Bilateral | 19 (79) |
| Single | 5 (21) |
| Immunosuppressive drugs | |
| TAC+MMF+MPD | 19 (79) |
| TAC+MPA+MPD | 2 (8) |
| TAC+RAP+MPD | 2 (8) |
| TAC+MPD | 1 (4) |
| Days from transplantation to positive culture (median [IQR]) | 64 [26–820] |
| Hospital admission | 11 (46) |
| ICU admission >48 h | 5 (21) |
| Antibiotics in the 3 previous mo | 20 (83) |
| BOS | 3 (13) |
| MPD intravenous pulses in the 3 previous mo | 2 (8) |
| Culture type | |
| BALF or BA | 19 (79) |
| Sputum | 4 (17) |
| Tracheal aspirate | 1 (4) |
| No. of positive cultures at diagnosis | |
| 1 | 10 (42) |
| 2 | 7 (29) |
| 3 | 5 (21) |
| 4 | 2 (8) |
| Culture | |
| Monomicrobial | 18 (79) |
| Polymicrobial | 6 (25) |
| Bronchoscopy performed | 19 (79) |
| Mucosal plaque | 10 (53) |
| Purulent secretions | 9 (47) |
a
BA, bronchial aspirate; BALF, bronchoalveolar lavage fluid; BOS, bronchiolitis obliterans syndrome; COPD, chronic obstructive pulmonary disease; ICU, intensive care unit; IPF, idiopathic pulmonary fibrosis; IQR, interquartile range; MMF, mycophenolate mofetil; MPA, mycophenolic acid; MPD, methylprednisolone; RAP, rapamycin; TAC, tacrolimus.