Table 1.
G894 T eNOS distribution Vs Clinical parameters
| eNOS | P value (< 0.05) | |||
|---|---|---|---|---|
| GG % | GT % | TT % | ||
| Age | 58.6 ± 9.34 | 61.77 ± 10.1 | 60.87 ± 10.25 | 0.07 |
| Gender | 0.4 | |||
| ♀ | 2.6 | 39.7 | 57.7 | |
| ♂ | 6.9 | 34.5 | 58.6 | |
| Ethnicity | 0.5 | |||
| White | 4.5 | 41 | 54.5 | |
| Metis | 3.4 | 34.8 | 61.8 | |
| Black | 0 | 58.3 | 41.7 | |
| Familial History of EH | 0.5 | |||
| yes | 4.5 | 39.8 | 55.7 | |
| no | 1.8 | 36.8 | 61.4 | |
| Familial History of CVD | 0.6 | |||
| yes | 5.9 | 38.2 | 55.9 | |
| no | 2.7 | 38.7 | 58.6 | |
| Familial History of Cerebrovascular disease | 0.9 | |||
| yes | 2.6 | 36.9 | 60.5 | |
| no | 3.7 | 39.3 | 57 | |
| Familial History of Diabetes | 0.3 | |||
| yes | 3.8 | 43.6 | 52.6 | |
| no | 3 | 32.8 | 64.2 | |
| Familial History of Renal disease | 0.8 | |||
| yes | 0 | 40 | 60 | |
| no | 3.7 | 38.5 | 57.8 | |
| Familial History of Dyslipidemia | 0.3 | |||
| yes | 4.7 | 30.2 | 65.1 | |
| no | 2.9 | 42.2 | 54.9 | |
| Smoking | 0.2 | |||
| yes | 7.7 | 53.8 | 38.5 | |
| no | 3 | 37.1 | 59.9 | |
| Alcohol | 0.009* | |||
| yes | 25 | 75 | 0 | |
| no | 2.8 | 37.6 | 59.6 | |
| Physical Activity | 0.05 | |||
| yes | 7.1 | 35.7 | 57.1 | |
| no | 0 | 41.3 | 58.7 | |
| Obesity | 0.02* | |||
| yes | 6.5 | 27.4 | 66.1 | |
| no | 1.2 | 47 | 51.8 | |
| Dyslipidemia | 0.9 | |||
| yes | 3.4 | 37.9 | 58.6 | |
| no | 3.4 | 39.1 | 57.5 | |
| Diabetes | 0.9 | |||
| yes | 3.8 | 37.7 | 58.5 | |
| no | 3.3 | 39.1 | 57.6 | |
| Menopausal status | 0.2 | |||
| yes | 3 | 32.8 | 64.2 | |
| no | 2 | 48 | 50 | |
| Personal History of CVD | 0.07 | |||
| yes | 9.7 | 29 | 61.3 | |
| no | 1.9 | 42.9 | 55.2 | |
| Nephropathy | 0.8 | |||
| yes | 0 | 33.3 | 66.7 | |
| no | 3.6 | 38.8 | 57.6 | |
| Nbr of antihypertensive molecules | 0.7 | |||
| 1 | 3.1 | 37.5 | 59.4 | |
| 2 | 5.1 | 42.3 | 52.6 | |
| 3 | 0 | 36 | 64 | |
| 4 | 0 | 22.2 | 77.8 | |
| TA | 0.7 | |||
| controled | 4.3 | 37.2 | 58.5 | |
| non-controled | 2 | 41.2 | 56.8 | |
| Neurological deficit | 0.7 | |||
| yes | 0 | 33.3 | 66.7 | |
| no | 3.7 | 39 | 57.3 | |
| Electrical HVG | 0.7 | |||
| yes | 0 | 38.5 | 61.5 | |
| no | 3.8 | 38.6 | 57.6 | |
| Repolarisation troubles | 0.5 | |||
| yes | 5.8 | 47.1 | 47.1 | |
| no | 3.1 | 37.5 | 59.4 | |
| Creatinine | 7.9 ± 4.14 | 11.38 ± 6.21 | 0.2 | |
| TG | 0.5 | |||
| ≤ 1 | 4.5 | 41 | 54.5 | |
| > 1 | 2.4 | 31.3 | 66.3 | |
| CT | 0.3 | |||
| ≤ 1 | 0 | 0 | 3 | |
| > 1 | 2.8 | 36.7 | 60.6 | |
| HDL | 0.8 | |||
| ≤ 0.5 | 2 | 36 | 62.8 | |
| > 0.5 | 3.8 | 32.1 | 64.2 | |
| LDL | 0.9 | |||
| ≤ 0.5 | 0 | 0 | 100 | |
| > 0.5 | 3 | 31 | 66 | |
| Glucose | 1.02 ± 0.48 | 1.18 ± 0.56 | 1.32 ± 0.6 | 0.9 |
| Na+ | 137 ± 28 | 139.6 ± 34.9 | 135.3 ± 20.6 | 0.3 |
| K+ | 4.1 ± 1.8 | 4.06 ± 1.9 | 4.22 ± 1.8 | 0.3 |
*Statistically significant; Nbr number, HVG left ventricular hypertrophy, GG Homozygous wild type, GT Heterozygous, TT Homozygous mutant