Table 3.
Allelic and genotypic distribution of G894 T eNOS polymorphism among cases and controls
| N = 145 | N = 184 | ||||
|---|---|---|---|---|---|
| Cases N(%) | Controls N(%) | OR [95% CI] | P value (< 0.05) | ||
| Genotypes | GG | 5 (3.49%) | 116 (63,04) | 1 | |
| GT | 54 (37.24%) | 62 (33,69) | 20.2 [7.7–52.4] | < 0.0001* | |
| TT | 86 (59.27%) | 6 (3,27) | 332.5 [98.2–1125.4] | < 0.0001* | |
| Dominant model | GG + GT | 59 (40.73%) | 178 (96,73) | 1 | |
| TT | 86 (59.27%) | 6 (3,27) | 43.2 [17.9–104.09] | < 0.0001* | |
| Recessive model | GG | 5 (3.49%) | 116 (63,04) | 1 | |
| GT + TT | 140 (96.51%) | 68 (36,96) | 47.7 [18.6–122.3] | < 0.0001* | |
| Additive model | G | 64 (22.07%) | 294 (79,89) | 1 | |
| T | 226 (77.93%) | 74 (20,11) | 14.02 [9.6–20.45] | < 0.0001* |
*Statistically significant; GG Homozygous wild type, GT Heterozygous, TT Homozygous mutant