Table 3.
Basic information of candidate SNPs in Tibetan subjects
| SNP_ID | Gene | Alleles A/B | Case (N) | Control (N) | OR (95% CI) | P | P1 | P2 | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AA | AB | BB | AA | AB | BB | |||||||
| rs7518602 | PIK3CD | C/T | 5 | 29 | 36 | 1 | 10 | 19 | 1.043 (0.438–2.490) | 0.612 | 0.240 | 0.238 |
| rs7516138 | PIK3CD | G/A | 11 | 26 | 33 | 3 | 13 | 14 | 1.015 (0.428–2.411) | 0.992 | 0.735 | 0.733 |
| rs7516214 | PIK3CD | G/A | 11 | 26 | 32 | 3 | 13 | 14 | 0.992 (0.416–2.366) | 0.982 | 0.688 | 0.691 |
| rs11805716 | PIK3CD | T/C | 15 | 27 | 17 | 6 | 8 | 13 | 1.061 (0.416–2.718) | 0.555 | 0.207 | 0.206 |
| rs11806839 | PIK3CD | G/C | 5 | 7 | 4 | 2 | 9 | 3 | 1.205 (0.270–5.393) | 0.893 | 0.593 | 0.612 |
| rs79190623 | PIK3CD | C/T | 58 | 10 | 1 | 18 | 11 | 1 | 0.862 (0.349–2.106) | 0.081 | 0.018 | 0.018 |
| rs72633866 | PIK3CD | G/A | 57 | 8 | 1 | 25 | 2 | 0 | 1.071 (0.434–2.656) | 0.791 | 0.366 | 0.367 |
| rs2230735 | PIK3CD | A/G | 59 | 10 | 1 | 17 | 12 | 1 | 0.844 (0.337–2.079) | 0.046 | 0.008 | 0.008 |
| rs182137610 | PIK3CD | A/C | 57 | 10 | 1 | 18 | 9 | 1 | 0.764 (0.301–1.897) | 0.150 | 0.050 | 0.045 |
| rs188191807 | PIK3CD | G/A | 53 | 5 | 1 | 22 | 5 | 0 | 0.685 (0.266–1.726) | 0.791 | 0.454 | 0.396 |
| rs28730671 | PIK3CD | C/T | 63 | 6 | 1 | 19 | 10 | 1 | 0.821 (0.324–2.035) | 0.046 | 0.007 | 0.007 |
| rs111888887 | PIK3CD | T/C | 61 | 6 | 1 | 21 | 8 | 1 | 0.906 (0.368–2.205) | 0.130 | 0.034 | 0.034 |
| rs9430220 | PIK3CD | T/C | 29 | 34 | 5 | 12 | 14 | 4 | 0.940 (0.395–2.234) | 0.851 | 0.536 | 0.535 |
| rs28730674 | PIK3CD | A/G | 63 | 6 | 1 | 19 | 10 | 1 | 0.821 (0.324–2.035) | 0.046 | 0.007 | 0.007 |
| rs371870925 | PIK3CD | T/C | 64 | 4 | 1 | 20 | 9 | 1 | 0.812 (0.320–2.017) | 0.046 | 0.007 | 0.007 |
| rs199962152 | PIK3CD | A/G | 58 | 4 | 1 | 19 | 6 | 1 | 0.685 (0.256–1.766) | 0.146 | 0.045 | 0.040 |
| rs77571929 | PIK3CD | T/C | 63 | 5 | 1 | 19 | 10 | 1 | 0.814 (0.320–2.024) | 0.046 | 0.005 | 0.005 |
| rs117226273 | PIK3CD | G/T | 63 | 6 | 1 | 19 | 10 | 1 | 0.821 (0.324–2.035) | 0.046 | 0.007 | 0.007 |
| rs28730676 | PIK3CD | T/C | 63 | 6 | 1 | 19 | 10 | 1 | 0.821 (0.324–2.035) | 0.046 | 0.007 | 0.007 |
| rs10864435 | PIK3CD | C/T | 55 | 15 | 0 | 25 | 4 | 1 | 1.011 (0.423–2.417) | 0.992 | 0.879 | 0.878 |
| rs28730677 | PIK3CD | G/A | 63 | 6 | 1 | 19 | 10 | 1 | 0.821 (0.324–2.035) | 0.046 | 0.007 | 0.007 |
| rs10178458 | COL4A3 | T/C | 4 | 21 | 45 | 4 | 7 | 19 | 1.026 (0.432–2.442) | 0.851 | 0.539 | 0.537 |
| rs6436669 | COL4A3 | A/G | 4 | 21 | 45 | 4 | 7 | 19 | 1.026 (0.432–2.442) | 0.851 | 0.539 | 0.537 |
| rs80109666 | COL4A3 | G/A | 60 | 9 | 1 | 28 | 2 | 0 | 1.070 (0.449–2.559) | 0.655 | 0.271 | 0.267 |
| rs55703767 | COL4A3 | G/T | 47 | 21 | 2 | 18 | 8 | 4 | 0.990 (0.415–2.360) | 0.524 | 0.184 | 0.184 |
| rs10205042 | COL4A3 | C/T | 0 | 23 | 47 | 4 | 8 | 18 | 1.017 (0.425–2.437) | 0.305 | 0.102 | 0.102 |
| rs34505188 | COL4A3 | G/A | 42 | 20 | 8 | 10 | 14 | 6 | 0.948 (0.390–2.292) | 0.115 | 0.028 | 0.028 |
| rs11677877 | COL4A3 | A/G | 42 | 21 | 7 | 10 | 13 | 7 | 0.941 (0.385–2.290) | 0.070 | 0.013 | 0.013 |
| rs34019152 | COL4A3 | G/A | 42 | 20 | 8 | 10 | 13 | 7 | 0.928 (0.380–2.254) | 0.081 | 0.018 | 0.018 |
| rs28381984 | COL4A3 | C/T | 24 | 39 | 7 | 23 | 6 | 1 | 0.761 (0.294–1.928) | 0.035 | 0.001 | 0.001 |
The abbreviations were the same as Table 2