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. 2018 Jul 27;9:201. doi: 10.1186/s13287-018-0947-5

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — The PiggyBac transposition system. The PiggyBac transposase has the ability to integrate into the genomic DNA of the host cell a DNA sequence provided that it is flanked by ITR sequences. The same PiggyBac transposase can in turn excise this inserted material, leaving the genomic DNA virally unchanged. ITR inverted terminal repeat