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. 2018 Jul 27;18:106. doi: 10.1186/s12935-018-0600-5

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Expression of p27 in different subgroups conjoining coilin levels for the prognosis of pediatric BCP-ALL. a Relative p27 expression at diagnosis (day 0) or complete remission (day 78) (n = 22). b Levels of p27 expression in patients of continuous complete remission (CCR) (n = 120) or relapse (n = 13). Analyses of c event free survival (EFS) and d relapse free survival (RFS) from the whole cohort of 144 BCP-ALL patients with high or low coilin expression. Analyses of e event free survival (EFS) and f relapse free survival (RFS) in patients with high or low p27 expression