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. 2018 Jul 27;19:139. doi: 10.1186/s12931-018-0847-3

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — The LRT microbiota of P. aeruginosa VAP patients was significantly different from that of the controls. Samples from day1 were collected for analysis. a The weighted unifrac distance between the LRT microbiota of each sample shown as a Pcoa two-dimensional map. Each dot represents one sample. b Shannon diversity index of the P. aeruginosa VAP group was significantly lower than those in the control group. c and d Histogram of lower respiratory tract microbial composition at phylum level (c) and at genus level (d) in P. aeruginosa VAP patients and control subjects. Data were presented as mean ± Standard deviation. The difference between groups was analyzed using the Mann-Whitney test, **P < 0.01. Control, control group; PAVAP, Pseudomonas aeruginosa VAP group