Table 6.
Pharmacological interactions among terpenes derived from L. alba
| Parasitic Form | Limonene + Compound | ΣFICf μg/mL ± SDg | Pharmacological interaction |
|---|---|---|---|
| Epia | CarOxd | 0.5 ± 0.13 | Synergism |
| Carvone | 1.1 ± 0.08 | Antagonism | |
| Citral | 0.7 ± 0.13 | Synergism | |
| BNZe | 0.4 ± 0.13 | Synergism | |
| Trypb | CarOxd | 0.4 ± 0.10 | Synergism |
| Carvone | 1.04 ± 0.04 | Antagonism | |
| Citral | 0.6 ± 0.10 | Synergism | |
| BNZe | 0.4 ± 0.10 | Synergism | |
| Amasc | CarOxd | 0.7 ± 0.23 | Synergism |
| Carvone | NDh | NDh | |
| Citral | 0.8 ± 0.15 | Synergism | |
| BNZe | 0.6 ± 0.13 | Synergism | |
| Vero | CarOxd | 1.2 ± 0.16 | Antagonism |
| Carvone | 1.0 ± 0.07 | Additive | |
| Citral | 1.0 ± 0.07 | Antagonism | |
| BNZe | 0.5 ± 0.18 | Synergism |
aEpi Epimastigote, bTryp Trypomastigote, cAmas Amastigote, dCarOx Caryophyllene oxide, eBNZ Benznidazole, fFIC Fractional inhibitory concentration, gSD Standard deviation, hND Not determinated