Table 3.
Genotypes of 6 SNPs
| Genotype | Girls | Boys | ||
|---|---|---|---|---|
| Prepuberty (%) | Precocoious puberty (%) | Prepuberty (%) | Precocious puberty (%) | |
| rs2239669a,b | ||||
| CC | 58 (62.4) | 4 (57.1) | 26 (59.1) | 9 (36.0) |
| CT | 28 (30.1) | 2 (28.6) | 17 (38.6) | 11 (44.0) |
| TT | 7 (7.5) | 1 (14.3) | 1 (2.3) | 5 (20.0) |
| rs6576457a,c | ||||
| GG | 59 (62.8) | 4 (57.1) | 26 (59.1) | 9 (34.6) |
| GA | 26 (27.7) | 2 (28.6) | 17 (38.6) | 11 (42.3) |
| AA | 9 (9.6) | 1 (14.3) | 1 (2.3) | 6 (23.1) |
| rs12441827d,e | ||||
| TT | 44 (45.80) | 2 (28.6) | 11 (25.0) | 17 (65.4) |
| TC | 38 (39.6) | 5 (71.4) | 30 (68.2) | 8 (30.8) |
| CC | 14 (14.6) | 0 (0) | 3 (6.8) | 1 (3.8) |
| rs12148769 | ||||
| GG | 51 (53.1) | 3 (42.9) | 21 (47.7) | 15 (57.7) |
| GA | 36 (37.5) | 3 (42.9) | 20 (45.5) | 11 (42.3) |
| AA | 9 (9.4) | 1 (14.3) | 3 (6.8) | 0 (0) |
| rs314276 | ||||
| CC | 55 (57.3) | 3 (42.9) | 27 (61.4) | 16 (61.5) |
| CA | 36 (37.5) | 3 (42.9) | 15 (34.1) | 7 (26.9) |
| AA | 5 (5.2) | 1 (14.3) | 2 (4.5) | 3 (11.5) |
| rs314280 | ||||
| AA | 5 (5.3) | 1 (14.3) | 2 (4.5) | 3 (11.5) |
| GA | 35 (36.8) | 3 (42.9) | 14 (31.8) | 7 (26.9) |
| GG | 55 (57.9) | 3 (42.9) | 28 (63.6) | 16 (61.5) |
aP < 0.01 for additive model (minor allele homozygotes versus heterozygotes) in boys
bP < 0.05 for recessive model in boys
cP < 0.01 for recessive model in boys
dP < 0.0001 for additive model (major allele homozygotes versus heterozygotes) in boys
eP < 0.01 for dominant model in boys