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. 2018 Jul 27;19:45. doi: 10.1186/s12868-018-0447-7

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Difference between ¹⁸F-florbetaben and ¹⁸F-flutemetamol in AD transgenic group. Each image represents PET image of a ¹⁸F-florbetaben (upper column), b ¹⁸F-flutemetamol (middle column) and c algebra calculation (¹⁸F-florbetaben-¹⁸F-flutemetamol, lower column). In the AD transgenic group, ¹⁸F-florbetaben showed higher and more extensive cortical uptakes compared with ¹⁸F-flutemetamol. Color scale bar represents 0–340 percentage of injected dose per cubic centimeter in ¹⁸F-florbetaben image. Color scale bar represents 0–270 percentage of injected dose per cubic centimeter in ¹⁸F-flutemetamol image. Color scale bar represents 0–280 percentage of injected dose per cubic centimeter in difference image