Fig. 6.

Dynamic PET time activity curves of the cortex-VOI and the cerebellum-VOI. Time-activity curves of a ¹⁸F-florbetaben in AD mouse, b ¹⁸F-florbetaben in control mouse, c ¹⁸F-flutemetamol in AD mouse, d ¹⁸F-flutemetamol in control mouse, were illustrated. Values are SUVbw (g/ml) for a cortex VOI (blue line) and a cerebellum VOI (black line). ¹⁸F-florbetaben showed higher initial uptake and later retention than did ¹⁸F-flutemetamol. In contrast, ¹⁸F-flutemetamol showed lower initial upstroke and faster washout than did ¹⁸F-florbetaben