Figure 6.

DCs loaded with the lysate of tumor cells infected with the NDV-TCL-DCs induced the production of IL-2 from CD4⁺ and CD8⁺ T cells. (A) A representative fluorescence activated cell sorting plot demonstrating the percentage of IL-2-positive cells among CD4⁺ and CD8⁺ T cells co-cultured with the three types of DCs. The percentage of IL-2-positive cells among (B) CD4⁺ and (C) CD8⁺ T cells co-cultured with the three types of DCs induced from peripheral blood monocytes of 12 patients with lung cancer. All error bars represent the mean ± standard deviation. *P<0.05; **P<0.01. CD4, cluster of differentiation 4; NDV-TCL-DCs, Newcastle Disease Virus-tumor cell lysate-dendritic cells; IL-2, interleukin-2; T, T cell.