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. 2018 May 11;16(1):1332–1340. doi: 10.3892/ol.2018.8705

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Figure 2. — The effect of IGF-1R knockdown combined with irradiation on apoptosis and radio-sensitivity in H520 cells. (A) CCK-8 assay analysis of proliferation in NC and stably transfected H520 cells treated using irradiation. *P<0.01 vs. the NC + irradiated (6 Gy) group. ***P<0.001 vs. the NC + irradiated (6 Gy) group. Data are presented as the mean ± SD. (B) Flow cytometric analysis of apoptosis rates in NC and stably infectedH520 cells treated using irradiation. **P<0.01 vs. the NC + irradiated (6 Gy) group. Data are presented as the mean ± SD. (C) Radiation dose-survival curves in NC and stably infected H520 cells treated using irradiation. ***P<0.001 vs. the NC + irradiated (6 Gy) group. Data are presented as the mean ± SD. IGF-1R, insulin-like growth factor-1 receptor; NC, negative control; SD, standard deviation.