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. 2018 Mar 15;131(24):2670–2681. doi: 10.1182/blood-2017-11-817601

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Figure 6. — Genetic alterations in TP53, TP63, and TP73 genes. (A) Mutations identified in TP53, TP63 and TP73 in HBsAg⁺ and HBsAg^- DLBCLs. (B-C) Diagram showing mutations identified in TP63 and TP73, respectively. (D) Alignment of the DNA-binding domain (DBD) of TP53, TP63, and TP73. OD, oligomerization domain; SAM, sterile α motif; TA, transactivation. (E) Characterization of transcriptional activity of mutant TP73. Data shown are from 3 independent experiments. Error bars represent standard deviation. ***P < .0001.