Figure 6.
SCFPROM-1 functions redundantly with GLD-1 to inhibit ectopic mitotic activity. (A) Images of 4-hr EdU labeled (green), costained for DNA (DAPI, cyan), germlines from dissected young-adult hermaphrodites of the indicated genotype. ☆ indicates distal gonadal end. Dashed red lines indicate position of overt meiotic entry. Solid yellow lines indicate zone of continuous EdU-labeled cells. Dotted white lines indicate proximal end of the germline. (B) Graph showing continuous EdU zone length, in cell diameters from the DT to the proximal end, for the indicated genotype of young-adult hermaphrodite germlines. Data are plotted as horizontal dot plots with each dot representing length in cell diameter for one gonad. Thick vertical lines represent mean and horizontal lines represent mean ± SD. P-value ≤ 0.01 (*); ≤ 0.001 (**); ≤ 0.0001 (***); > 0.01 non-significant (NS.). WT, wild type.