Table 2. Wild type LRRK2 top association candidate genes.
Rank | SNPa | Candidate gene | P-value | Human ortholog | OMIM |
---|---|---|---|---|---|
1 | 3L:10050040 | dpr6 | 3.88E−07 | — | — |
2 | 3L:21397373 | rgn | 1.49E−06 | REG1A | 167770 |
3 | 3R:27842339 | CR45557 | 1.58E−06 | — | — |
4 | 3R:27651356 | RhoGAP100F | 1.90E−06 | SYDE1 | 617377 |
5 | X:18889282 | CG43759 | 2.37E−06 | — | — |
6 | X:19061795 | Inx5 | 3.91E−06 | — | — |
7 | 2R:8429948 | fra | 4.70E−06 | NEO1 | 601907 |
8 | 2R:13961559 | CG34386 | 7.87E−06 | — | — |
9 | X:9100745 | SmydA-9 | 7.97E−06 | SMYD2 | 610663 |
10 | 2R:15036909 | ena | 8.37E−06 | ENAH | 609061 |
11 | 3R:27805736 | heph | 9.65E−06 | PTBP1 | 600693 |
12 | X:5248137 | sk | 9.86E−06 | — | — |
SNP with most statistically significant association for the candidate gene.