Fig. 2.
Chromosomal distribution of CAPs. (a) The distribution of candidate adaptive alleles (CAPs) across autosomal chromosomes (red points). Chromosomal banding patterns are also visualized for reference. (b) A plot of −log10(Pneu) generated from the Evolutionary Probability Approach (y axis) against chromosome position (x axis) for the MHC region of chromosome 6. CAPs are shaded red and non-CAPs are shaded gray. The CAP Pneu cutoff is shown with a dashed red line. Notable HLA genes with >20 CAPs are indicated.