Fig 4. Dependence of L-asparaginase catalytic activity on the degree of PEGylation.

Relative catalytic activity is expressed as percentage compared to the non-conjugated L-asparaginase defined as 100% and reported by each study. Modification degree refers to the average percentage of conjugated sites relative to the available amine groups per L-asparaginase tetramer. The results to generate this figure were extracted from references [16–22,34] and this work.