Table 1. Catalytic activity of cysteine-directed crosslinked L-asparaginase.

Sample	Specific activity (U/mg)	Relative activity (%)a
Native	161 ± 9	100
A38C-T263C	116 ± 6	72 ± 6
5kDa-PEG-conjugate	210 ± 11	130 ± 11
Randomly-PEGylatedb	125 ± 10	77 ± 8

^aSpecific activity of native L-asparaginase was defined as 100%.

^bCommercial randomly-PEGylated L-asparaginase formulation (Millipore Sigma, USA) was used for comparison.

Reported values are the average with the standard deviation calculated by error propagation.