Table 5a. Analyses of Opioid Misuse as a Predictor of Latent Drinking Profiles at the End of Treatment (Month 4), with Infrequent Drinking (Profile 3) as the Reference Class.

Frequent Heavy Drinking Profile Month 4	OR	B (SE)
Baseline opioid use (misuse = 1)	2.90	1.07 (0.36)**
Baseline drug use (use = 1)	2.36	0.86 (0.29)**
Baseline cannabis use (use = 1)	2.35	0.86 (0.26)**
Baseline pain scores	1.07	0.07 (0.14)
Baseline percent heavy drinking days	1.03	0.03 (0.005)**
Baseline maximum drinks	0.99	-0.001 (0.01)
Alcohol dependence severity (ADS)	1.02	0.02 (0.02)
Motivation to change (URICA)	0.96	-0.05 (0.07)
Temptation (AASE-Withdrawal temptation)	0.83	-0.18 (0.15)
Self-efficacy (AASE-Confidence)	0.88	-0.12 (0.23)
Psychiatric distress (BSI GSI)	1.002	0.002 (0.02)
Therapy (Combined behavioral intervention=1)	0.68	-0.42 (0.22)
Medication (Naltrexone=1)	0.56	-0.58 (0.19)**
Gender (Male=1)	0.71	-0.34 (0.30)
Cigarettes per day	1.01	0.01 (0.007)
Occasional Heavy Drinking Profile Month 4	OR	B (SE)
Baseline opioid use (misuse=1)	0.99	-0.12 (0.33)
Baseline drug use (use = 1)	2.10	0.74 (0.18)**
Baseline cannabis use (use = 1)	1.42	0.35 (0.25)
Baseline pain scores	1.16	0.15 (0.13)
Baseline percent heavy drinking days	1.00	0.000 (0.01)
Baseline maximum drinks	0.99	-0.007 (0.01)
Alcohol dependence severity (ADS)	1.02	0.02 (0.01)*
Motivation to change (URICA)	0.89	-0.11 (0.08)
Temptation (AASE-Withdrawal temptation)	0.90	-0.11 (0.13)
Self-efficacy (AASE-Confidence)	0.65	-0.43 (0.17)*
Psychiatric distress (BSI GSI)	1.01	0.01 (0.01)
Therapy (Combined behavioral intervention=1)	0.75	-0.29 (0.18)
Medication (Naltrexone=1)	0.64	-0.45 (0.15)**
Gender (Male=1)	1.01	0.01 (0.18)
Cigarettes per day	1.01	0.01 (0.01)

Note.

^*p<0.05;

^**p<0.01;

¹reference class is Class 3, infrequent drinking class; OR=odds ratio; B=unstandardized regression coefficient (SE=Standard Error)