Table 2. Association of adipose tissue and muscle measures and tumor recurrence.
Data are presented as hazard ratio (95% CI) per 1 SD increase in cm2 and HU, respectively.
VAT CSA (cm2) | p | VAT attenuation (HU) | p | SAT CSA (cm2) | p | SAT attenuation (HU) | p | Psoas attenuation (HU) | p | |
---|---|---|---|---|---|---|---|---|---|---|
No Covariates | 1.00 (0.99–1.00) | 0.9 | 1.00 (0.96–1.04) | 1.0 | 1.00 (1.00–1.00) | 0.4 | 1.07 (1.03–1.11) | 0.001 | 0.92 (0.89–0.96) | 0.0002 |
Model 1 | 0.99 (0.99–1.00) | 0.07 | 1.02 (0.97–1.07) | 0.4 | 1.00 (0.99–1.00) | 0.08 | 1.09 (1.04–1.13) | 0.0002 | 0.92 (0.89–0.96) | 0.0002 |
Model 2 | 0.99 (0.98–1.00) | 0.09 | 1.01 (0.94–1.07) | 0.8 | 0.99 (0.99–1.00) | 0.5 | 1.12 (1.04–1.22) | 0.002 | 0.92 (0.86–0.98) | 0.01 |
Model 3 | 1.00 (0.99–1.01) | 0.7 | 1.03 (0.96–1.11 ) | 0.4 | 1.01 (0.99–1.01) | 0.2 | 1.10 (1.01–1.19) | 0.02 | 0.89 (0.82–0.97) | 0.004 |
Model 1 Adjusted for age and comorbidities
Model 2 Adjusted for Model 1 plus sarcoma type, size, and stage.
Model 3 Adjusted for Model 2 plus pre- operative radiation dose and positive resection margins
VAT = visceral adipose tissue; CSA = cross-sectional area; SAT = subcutaneous adipose tissue;