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. Author manuscript; available in PMC: 2018 Jul 27.
Published in final edited form as: Biomacromolecules. 2017 Sep 14;18(10):3040–3051. doi: 10.1021/acs.biomac.7b00324

Figure 3.

Figure 3

Regulation of glioblastoma cell stiffness by substrate stiffness and composition. (A) Cell stiffness as a function of substrate stiffness for polyacrylamide hydrogels coated with collagen I or laminin. (B) Differences in the cell stiffness when PAA is substituted with HA. (C) Glioblastoma cell stiffness as a function of their spreading area. The unpaired Student’s t test was used to confirm statistical differences between the cell stiffness in panels A (between 0.3 and 14 kPa PAA gels) and B (between 0.3 kPa PAA and 0.3 kPa HA); denotation: ***, P < 0.00).