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. Author manuscript; available in PMC: 2019 Jan 23.
Published in final edited form as: Nat Neurosci. 2018 Jul 23;21(8):1126–1136. doi: 10.1038/s41593-018-0187-0

Figure 2. Functional enrichment of non-overlapping cell- and tissue-specific histone peaks.

Figure 2

(A) Venn diagrams showing overlap in Mb of peak regions between neuronal (blue), non-neuronal (gold) and homogenate (black) for H3K4me3 (left panel) and H3K27ac (right panel). (B) Functional enrichments evaluated using GREAT 19 of peak regions that are unique to each of the 3 sets. Bar plots in blue, gold and black correspond to –log10 p-value from hypergeometric test of pathway enrichment results of peaks that are unique to neuronal, non-neuronal and homogenate respectively. H3K4me3, N (brains) = 17 PFC NeuN+, 17 PFC NeuN−, 11 PFC tissue homogenate, and H3K27ac N (brains) = 17 PFC NeuN+, 17 PFC NeuN−, 17 PFC tissue homogenate.