. Author manuscript; available in PMC: 2019 Aug 1.

Published in final edited form as: Clin Genitourin Cancer. 2018 Feb 5;16(4):e761–e769. doi: 10.1016/j.clgc.2018.01.011

Table 5.

Univariate Predictors of 10-year FRS in Testicular Cancer Survivors

Sociodemographic Characteristic	Patients, n	Crude Model^a		Adjusted Model^a
Sociodemographic Characteristic	Patients, n	Mean FRS^b	P^c	Adjusted LSMEANS of FRS^b	P^c
Race^d
White	684	4.79		4.63
Nonwhite^e	98	2.96	<.001	4.46	.34
Education^f
Less than college graduate^g	254	4.83		5.07
College graduate or postgraduate^h	523	4.36	.15	4.39	<.001
Marital statusⁱ
Single/divorced/separated	286	2.78		4.64
Married/living as married	492	5.94	<.001	4.57	.63
Vigorous physical activity (≥6 METs)^j
No	232	6.54		4.92
Yes	552	3.83	<.001	4.45	<.001
Chemotherapy regimen
EP	284	4.85		4.64
BEP	503	4.31	.09	4.59	.81
Chemotherapy regimen, no. cycles
EP	284	4.85	Re^k	4.67	Ref^k
BEP ≤ 3 cycles	342	4.32	.26	4.54	.81
BEP ≥ 4 cycles	161	4.30	.38	4.70	.98

Abbreviations: BEP = bleomycin, etoposide, and cisplatin; EP = etoposide and cisplatin; FRS = Framingham Risk Score; IU = International Units; LSMEANS = Least Square Means (adjusted means); MET = metabolic equivalent of task; Ref = reference.

Crude results are from univariate analysis; adjusted models are adjusted for cancer center and log-transformed age (continuous variable) using LSMEANS.

Both crude means and LSMEANS are calculated for log-transformed FRS and then exponentiated to original scale.

P-values are calculated from the General Linear Model.

Five patients did not state their race.

The 98 nonwhite participants include 7 Black/African American, 34 Asian, 1 Native Hawaiian Pacific Islander, 1 American Indian, 30 other, 15 who declined to answer (or unknown race), and 10 who designated more than one race.

Ten patients had other educational status or did not report it.

Includes 79 patients with high school or less and 175 patients with training after high school or some college.

Includes 351 patients who were college graduates and 172 patients who completed postgraduate training.

ⁱ

Nine patients did not report marital status.

Three patients had missing data on physical activity.

All pairwise differences were tested using the Tukey-Kramer post-hoc adjustment method. P-values reported in the table are for pairwise comparisons between each category and a specified reference category.