Fig. 2.

Example dataset showing coronal PET maximum intensity projections (MIP) of the pelvic frame. PSMA accumulation is seen in the left ureter; besides the high activity in the primary tumor (green arrow), a small lymph node can be detected (red arrow). The reconstructions are TOF OSEM with 28 subsets and 2 (a), 3 (b), and 8 (c) iterations; TOF BSREM with regularization parameter β = 150 (d), 200 (e), 250 (f), 300 (g), 350 (h), 400 (i), 450 (j), 500 (k), 550 (l), 600 (m), 700 (n), 800 (o), 900 (p), 1000 (q), and 1200 (r). All images have SUV scale 0–10 g/ml. SUV standardized uptake value, TOF time-of-flight, OSEM ordered subset expectation maximization, BSREM block sequential regularized expectation maximization