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. 2018 May 21;35(7):1339–1348. doi: 10.1007/s10815-018-1183-8

Table 3.

Comparison of kinetic timings for embryo development in patients using surgically retrieved sperm, PESA or TESE versus control sperm (CS) isolated from semen of non-male factor patients

Patient group Control (CS) (n = 209) 95% CI PESA (n = 175) 95% CI TESE (n = 210) 95% CI P value
Parameter Mean (h) Mean (h) Mean (h)
t2 26.3 25.7–26.9 26.1 25.4–26.7 27.1 26.5–27.7 < 0.05a
t3 36.0 35.0–36.9 35.3 34.2–36.3 36.5 35.6–37.5 NS
t4 38.0 37.2–38.9 37.3 36.3–38.2 39.1 38.2–39.9 < 0.05a
t5 48.6 47.2–49.9 46.8 45.4–48.3 48.6 47.2–50.0 NS
t8 58.9 57.4–60.4 58.0 56.3–59.8 60.5 58.7–62.4 < 0.05a
CP 67.6 65.3–69.8 63.8 61.3–66.3 69.1 66.5–71.8 < 0.05ac
tM 91.9 90.3–93.6 92.2 90.3–94.1 91.1 88.8–93.3 NS
tSB 101.2 99.6–102.8 101.4 99.5–103.3 103.5 101.6–105.4 NS
tB 106.2 104.6–107.9 107.3 105.4–109.3 108.5 106.2–110.7 NS
tEB 114.3 112.4–116.2 114.4 112.2–116.6 115.8 113.2–118.5 NS
t3-t2 (cc2) 9.7 8.8–10.7 10.6 9.5–11.7 10.8 9.8–11.8 NS
t4-t3 (s2) 2.1 1.6–2.5 2.6 1.8–3.5 4.8 3.6–6.0 < 0.05ab
t5-t3 (cc3) 12.7 11.6–13.8 12.2 11.0–13.4 14.5 13.4–15.7 < 0.05ab

P value < 0.05 considered to be statistically significant

aTESE vs PESA bTESE vs CS cPESA vs CS