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. 2018 Jul 27;8:11365. doi: 10.1038/s41598-018-29735-6

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Serum ALT levels of “FFA-high and EAA-high” patients showed high serum ALT. Correlations between serum FFA levels, whole blood EAA and serum ALT levels were analyzed in 127 patients with NAFLD (fibrosis stages 0, 1 and 2). (A) Serum FFA, whole blood EAA and serum ALT were plotted in three dimensions. “FFA-high and EAA-high” group is red. “FFA-low and EAA-low”, “FFA-low and EAA-high” and “FFA-high and EAA-low” groups are blue. Ellipsoid means cumulative probability = 0.75. (B) Serum ALT levels of “FFA-low and EAA-low (n = 45)”, “FFA-low and EAA-high (n = 36)”, “FFA-high and EAA-low (n = 25)” and “FFA-high and EAA-high (n = 21)” groups were analyzed. Results are presented as means ± SD. *P < 0.05 compared with “FFA-low, EAA-low”. ^#P < 0.05 compared with “FFA-low, EAA-high”. ^$P < 0.05 compared with “FFA-high, EAA-low”. NS, not significant compared with “FFA-low, EAA-low”.