Table 1.

Correlations between histopathologic features of liver biopsies and clinical parameters in patients with NAFLD.

N = 498		steatosis	Lobular inflammation	ballooning	fibrosis
Body mass index	r	0.148	0.099	0.122	0.116
	p	0.001	0.028	0.007	0.010
Platelet count	r	0.137	−0.047	−0.009	−0.235
	p	0.002	0.292	0.841	1.12 × 10−7
AST	r	0.198	0.346	0.271	0.348
	p	8.92 × 10−6	1.71 × 10−15	7.53 × 10−10	1.19 × 10−15
ALT	r	0.302	0.270	0.250	0.117
	p	5.52 × 10−12	9.07 × 10−10	1.55 × 10−8	0.009
Total cholesterol	r	0.057	0.025	0.029	−0.141
	p	0.207	0.576	0.514	0.002
Triglyceride	r	0.161	−0.040	0.057	−0.159
	p	3.18 × 10−4	0.372	0.208	3.53 × 10−4
HDL cholesterol	r	−0.078	0.019	0.002	0.041
	p	0.081	0.669	0.957	0.362
LDL cholesterol	r	0.038	0.032	0.055	−0.114
	p	0.394	0.470	0.217	0.011
Free fatty acid	r	−0.086	0.077	0.017	0.204
	p	0.054	0.085	0.708	4.60 × 10−6
Type IV collagen 7S	r	0.142	0.244	0.244	0.386
	p	0.002	3.31 × 10−8	3.42 × 10−8	3.72 × 10−19
Hyaluronic acid	r	−0.080	0.116	0.098	0.309
	p	0.073	0.009	0.029	1.76 × 10−12

Spearman’s rank correlation coefficient.

AST, aspartate aminotransferase; ALT, alanine aminotransferase; HDL, high-density lipoprotein; LDL, low-density lipoprotein.

Results are presented as means ± SD.

P < 0.05 for comparisons between groups using Spearman’s rank correlation coefficient.