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. 2018 Jul 27;8:11376. doi: 10.1038/s41598-018-29662-6

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Gene interaction analysis [co-expression (purple), co-localization (light blue), physical interactions (orange), genetic interactions (green) and consolidated pathways (grey)] performed with F. candida’s differentially expressed transcripts after exposure to the herbicide formulation for 10 days. Protein domain attributes and genes related to query genes are presented in grey nodes and query genes presented in black nodes. Interaction analysis was performed with the list of Drosophila melanogaster genome homologous genes to F. candida, using GeneMANIA plugin from Cytoscape software (version 3.4.0).