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. 2018 Jul 27;8:11356. doi: 10.1038/s41598-018-29687-x

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Abundance distribution of co-abundance groups (CAGs). (A) Distribution of the relative abundance of each CAG in the studied population (n = 441). (B–F) Principal coordinate analysis (PCoA) based on weighted UniFrac distances describing the enterogradient of the studied population (n = 441). The different panels show the same cloud point colored by the relative abundance of each co-abundance group (CAG). (B) Prevotella-CAG, (C) Lachnospiraceae-CAG, (D) Pathogen-CAG, (E) Akkermansia-Bacteroidales-CAG, (F) Ruminococcaceae-CAG. Percentages on the axes represent the proportion of the explained variation of each component of the PCoA. Note the change in the relative abundance scale among panels.