Figure 5.

Schematic presentation of the imaging and analysis procedure. Two transversal planes of each tumour were recorded over time. Shortly after the image acquisition was started, microbubbles were injected as a bolus. A high mechanical index destruction pulse was applied and the replenishment of microbubbles was recorded. The raw RF B-mode data was post-processed to enable feature extraction. All extracted features were then fed into the feature selection process to generate a radiomics signature, which can be used for classification.