. 2018 Jul 27;8:11377. doi: 10.1038/s41598-018-29063-9

Table 3.

Effect of annatto-extracted tocotrienol supplementation on liver mRNA expression.

Variables (Target, x10³/cyclophilin)	LFD	HFD	T400	T1600	Met	P value
IL-2	2.00^b ± 0.43	12.70^a ± 4.00	1.91^b ± 0.27	2.22^b ± 0.30	2.15^b ± 0.27	<0.001
IL-23	9.40^b ± 1.61	25.50^a ± 9.79	6.39^b ± 1.21	7.66^b ± 1.42	5.68^b ± 0.89	0.023
IFN-γ	6.14^b ± 1.47	28.50^a ± 10.70	6.85^b ± 1.43	8.59^b ± 2.46	8.18^b ± 2.44	0.013
MCP-1	12.10^b ± 1.66	34.10^a ± 7.07	13.20^b ± 1.59	13.30^b ± 2.46	15.70^b ± 7.06	0.016
ITGAX	0.92^b ± 0.21	2.89^a ± 1.06	1.05^b ± 0.19	1.28^b ± 0.29	1.17^b ± 0.23	0.028
F4/80	5.94^b ± 0.82	12.70^a ± 3.28	5.19^b ± 1.08	5.41^b ± 1.23	5.71^b ± 0.88	0.014

Data are mean ± SEM. Within the same row, values not sharing a common letter are statistically different (p < 0.05). IFN-γ, interferon-γ; IL, interleukin; ITGAX, integrin subunit alpha x; MCP-1, monocyte chemoattractant protein-1.