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Trapezoidal AUC for GH during OGTTs at baseline and week 14. In the twice-weekly cohort, the median increase in AUC was 46% at week 14 compared to baseline (P = 0.001). There was no change in GH levels in the once-weekly cohort. AUC, area under the curve; GH, growth hormone; OGTT, oral glucose tolerance test.
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