Table 2.

Univariate analysis for various factors related to overall survival (OS)

Characteristic	survival					P value
	n/N	Median survival time (years)	1 year (%)	3 years (%)	5 years (%)
Overall rate	22/39	3.89	69.1	50.5	41.2
Gender
Male	11/21	5.11	71.4	60.3	46.5	0.269
Female	11/18	1.34	66.2	19.3	19.3
Mean age (years)
≤ 63	11/18	1.65	55.0	40.1	30.0	0.516
>  63	11/21	5.35	76.2	51.9	41.5
Mean duration of presenting symptom (weeks)
≤ 67.9	16/26	3.89	65.2	51.8	41.5	0.967
>  67.9	6/13	1.70	69.2	48.5	48.5
Restriction of extraocular movements
No	4/10	5.35	90.0	75.0	56.0	0.093
Yes	18/29	1.65	58.0	36.2	29.0
Mass
No	6/13	5.35	69.2	29.7	29.7	0.965
Yes	16/26	3.01	69.2	49.0	37.8
Eye pain on presentation
No	13/23	3.01	69.6	55.8	42.5	0.646
Yes	9/16	3.89	68.8	40.1	20.1
VA
≥ 20/400	3/12	10.1	91.7	68.8	68.8	0.018*
<  20/400	18/26	1.65	57.4	38.1	30.5
Tumor size
≤ 20 mm	4/13	11.95	76.2	67.7	67.7	0.032*
>  20 mm	18/26	1.65	65.4	41.4	27.6
Histopathologic diagnosis
Non-squamous cell carcinoma	15/25	3.01	63.8	43.8	37.6	0.528
Squamous cell carcinoma	7/14	5.35	78.6	50.3	25.1
Tumor origin
Lid	6/12	3.01	83.3	44.4	22.2	0.660
Lacrimal, globe, and orbit	8/14	0.85	50.0	40.0	40.0
Conjunctiva	8/13	5.11	69.2	52.8	39.6
Surgical margins
Unclear margin	7/14	5.45	71.4	52.1	39.1	0.597
Clear margin	15/25	3.89	68.0	44.1	35.3
Tumor invasiveness (lymphovascular, perineural, bony)
No	15/29	3.89	65.5	48.6	41.7	0.453
Yes	7/10	3.01	80.0	40.0	20.0
Status of metastasis
No distant metastasis	9/23	5.45	91.3	70.6	62.8	<  0.001*
Regional nodal metastasis	3/5	3.01	60.0	60.0	0.0
Distant metastasis	10/11	0.59	24.2	0.0	0.0
Adding resection
No	18/33	3.89	63.5	47.9	41.9	0.815
Yes	4/6	3.01	83.3	33.3	0.0
Radiation
No	12/22	3.89	72.7	52.0	36.4	0.579
Yes	10/17	5.11	64.7	37.8	37.8
Chemotherapy
No	16/31	3.89	77.3	53.5	41.3	0.197
Yes	6/8	0.65	37.5	18.8	18.8
Recurrent disease
No	16/32	5.35	74.9	55.5	44.1	0.043*
Yes	6/7	0.85	28.6	0.0	0.0

n deceased patients, N total patients, VA Visual acuity, *P value < 0.05