Table 2.

Univariate and multivariate Cox regression analysis of clinical pathologic features for OS in CGGA cohort

Characteristics	Univariate analysis			Multivariate analysis
	HR	95% CI	P-value	HR	95% CI	P-value
Age	1.038	1.022–1.053	<0.001	1.004	0.987–1.022	0.637
Gender	0.843	0.597–1.189	0.33
Grade	3.469	2.709–4.443	<0.001	1.978	1.371–2.854	<0.001
Subtype	0.583	0.492–0.691	<0.001	0.869	0.711–1.062	0.17
IDH	0.229	0.159–0.331	<0.001	0.909	0.492–1.677	0.759
MGMT promoter	0.529	0.374–0.75	<0.001	0.773	0.511–1.169	0.222
1p/19q	0.165	0.067–0.404	<0.001	0.608	0.234–1.58	0.307
WDFY3-AS2	0.374	0.311–0.449	<0.001	0.571	0.423–0.771	<0.001

HR hazard ratio, CI confidence interval, IDH isocitrate dehydrogenase, MGMT methylguanine methyltransferase