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. 2018 Jul 28;18:353. doi: 10.1186/s12879-018-3220-8

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Trajectory of FLU-PRO scores from pre-challenge to Day 10 post-challenge. Mean FLU-PRO scores from Day − 1 (pre-inoculation) through Day 10 by FLU-PRO domains and total scores. Peak FLU-PRO scores occurred on Day 3 for Nose, Body/Systemic, Throat, and Gastrointestinal domains and total score. Peak FLU-PRO scores occurred on Day 4 for Eyes and Chest/Respiratory domains