Table 2.
Mean (SE) FLU-PRO domain and total scores on Day 3 by baseline (Day 0) joint HAI/NAI status
| FLU-PRO Total/Domain Score | High HAI – High NAIa | Low HAI – High NAIa | Low HAI – Low NAIa | Overall F value (P value)b | Pairwise Comparisonc | |||
|---|---|---|---|---|---|---|---|---|
| N | LS Mean (SE) | N | LS Mean (SE) | N | LS Mean (SE) | |||
| Daily Mean | ||||||||
| Total Score | 22 | 0.07 (0.04) | 29 | 0.09 (0.04) | 10 | 0.45 (0.06) | 13.87 (<.0001) | 1: 0.9599 |
| 2: < 0.0001 | ||||||||
| 3: < 0.0001 | ||||||||
| Nose | 22 | 0.18 (0.10) | 29 | 0.21 (0.08) | 10 | 1.13 (0.14) | 17.88 (<.0001) | 1: 0.9713 |
| 2: < 0.0001 | ||||||||
| 3: < 0.0001 | ||||||||
| Throat | 22 | 0.08 (0.05) | 29 | 0.11 (0.04) | 10 | 0.35 (0.07) | 6.07 (0.0040) | 1: 0.8095 |
| 2: 0.0055 | ||||||||
| 3: 0.0148 | ||||||||
| Eyes | 22 | 0.05 (0.06) | 29 | 0.05 (0.05) | 10 | 0.33 (0.09) | 4.14 (0.0209) | 1: 0.9962 |
| 2: 0.0437 | ||||||||
| 3: 0.0292 | ||||||||
| Chest/Respiratory | 22 | 0.05 (0.04) | 29 | 0.08 (0.04) | 10 | 0.26 (0.07) | 3.69 (0.0310) | 1: 0.8958 |
| 2: 0.0386 | ||||||||
| 3: 0.0689 | ||||||||
| Gastrointestinal | 22 | 0.04 (0.03) | 29 | 0.01 (0.02) | 10 | 0.13 (0.04) | 2.65 (0.0792) | 1: 0.7754 |
| 2: 0.2510 | ||||||||
| 3: 0.0794 | ||||||||
| Body/Systemic | 22 | 0.07 (0.06) | 29 | 0.09 (0.05) | 10 | 0.49 (0.08) | 10.49 (0.0001) | 1: 0.9666 |
| 2: 0.0004 | ||||||||
| 3: 0.0004 | ||||||||
aHigh HAI - High NAI: HAI > = 1:40 and NAI > = 1:40; Low HAI – High NAI: HAI < 1:40 and NAI > = 1:40; Low HAI – Low NAI: HAI < 1:40 and NAI < 1:40
bAn analysis of Variance (ANOVA) model
cComparing mean FLU-PRO total/domain scores, 1: group 1 vs. group 2, 2: group 1 vs. group 3, 3: group 2 vs. group 3