Skip to main content
. Author manuscript; available in PMC: 2018 Jul 28.
Published in final edited form as: Acta Physiol (Oxf). 2017 Oct 23;222(2):10.1111/apha.12963. doi: 10.1111/apha.12963

FIGURE 5.

FIGURE 5

Central administration of orexin A stimulates the expression of proinflammatory cytokines (PICs) in the PVN of SD rats. Real-time PCR analysis of paraventricular nucleus (PVN) PICs mRNA expression levels at 3 hours following acute intracerebroventricular (ICV) infusion of vehicle control (0.9% saline) or orexin A (0.2 nmol) using male adult SD rats. ICV injection of orexin A increases PVN IL-1-β, IL-6, TNF-α and Fra1 mRNA expression in SD rats. The mRNA level in the control sample was assigned to be arbitrary unit (a.u). *P < .05 vs vehicle control; n = 6 each group