Skip to main content
. 2018 Jul 25;6:e5263. doi: 10.7717/peerj.5263

Table 4. In vitro activities of antifungals and tigecycline combinations against biofilm formation 2–8×, 2–8 fold decrease in SMIC.

(+)2–8 fold increase in SMIC.

Interactions on biofilm formation in MIC
AMB FLC ITC ANI CAS
D/I  µg ml−1 D/I µg ml−1 D/I  µg ml−1 D/I µg ml−1 D/I µg ml−1
C.albicans 1 0.25 (+)2× 1 0.25 0.06 0.06
C.albicans 2 0.125 0.25 0.125 0.125 (+)2× 0.001
C.albicans 3 0.5 0.5 0.25 0.03 0.03
C.albicans 4 0.125 0.25 0.125 0.015 0.001
C.albicans SC5314 0.25 0.5 0.25 0.015 0.125

Notes.

D/I: Decrease or Increase 1×, no significant decrease; 2–8×, 2–8 fold decrease in MIC. (+)2 fold increase in MIC

AMB
Amphotericin B
FLC
Fluconazole
ITC
Itraconazole
ANI
Anidulafungin
CAS
Caspofungin